PCR Babesia
BABE: Request Form from EU
BABE: Request Form from USA
Sample required: Blood: 2 ml whole blood in EDTA tube. Stable for 48hours. For longer periods freeze at –20°C or –80°C
PCR Bartonella
Bart: Request Form from EU
Bart: Request Form from USA
Sample required: Blood: 2 ml whole blood in EDTA tube. Stable for 48hours. For longer periods freeze at –20°C or –80°C


TH1/Th2 balance urine tests
The Urine Balance Test aims at detecting alterations of the Th1/Th2 balance. The test allows patients and doctors to follow-up on Th1/Th2 balance during therapy and to evaluate whether the treatment is really effective.
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Urine Kit Ordering Form from EU
Urine Kit Ordering Form from USA
Cytokine RNA, inflammatory

A principal avenue of investigation has been the measurement in blood of immune signals conducted by cytokines.
In animal studies, administration of pro-inflammatory cytokines (IL-1, TNF-α, and IL-6) directly into the brain can induce "sickness behaviors" that strongly resemble the symptoms of CFS. In particular, decreased motor activity, altered food and water intake, sleep and cognition have been linked to

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CYTI: Request Form from EU
CYTI: Request Form from USA
Samples: RNA-based tests : One TempusTM tube. Stable for 72 hours at ambient temperature. For longer periods freeze and ship at -20°C
High-sensitivity C-reactive Protein (hs-CRP)
C-reactive protein (CRP) is a biomarker of inflammation. Plasma CRP concentrations increase rapidly and dramatically (100-fold or more) in response to tissue injury or inflammation.
hs-CRP: Request Form from EU
hs-CRP: Request Form from USA
Serum-based tests : 2 ml SERUM. Centrifuge immediately after clotting. Keep at ambient temperature or 4°C for 24h. For longer periods, aliquot, freeze and ship frozen.

Perforin expression assay (PERF)
Natural Killer cells (NK) are cytotoxic cells that mediate the immune response against certain cancer and virus-infected cells. NK cells are normally found in the peripheral blood and are classified by their cell surface markers such as CD3-/CD56+ cells.
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PERF: Request Form from EU
PERF: Request Form from USA
RNA-based tests : One TempusTM tube. Stable for 72 hours at ambient temperature. For longer periods freeze and ship at -20°C
Elastase expression assay (ELAS)
Elastase is an inflammatory protease expressed in immune cells. Elastase contributes to the immune defense by inactivating foreign bacteria but causes damage to connective tissue and breaks down cytokines, immunoglobulins and immune cells receptors at the same time.
ELAS: Request Form from EU
ELAS: Request Form from USA
RNA-based tests : One TempusTM tube. Stable for 72 hours at ambient temperature. For longer periods freeze and ship at -20°C

Immunoblot for autoantibodies (ANA/ENA)
ANA/ENA IgG immunoblot with 15 antigens is an immunoblot for autoantibodies in Connective Tissue Diseases CTD - Systemic lupus erythematosus (SLE), Sjögren´s syndrom (SjS), Mixed connective tissue disease (MCTD),
ANA/ENA: Request Form from EU
ANA/ENA: Request Form from USA
Serum-based tests : 2 ml SERUM. Centrifuge immediately after clotting. Keep at ambient temperature or 4°C for 24h. For longer periods, aliquot, freeze and ship frozen.

Autoantibodies for neuronal antigens (AA-Neuro)
AA-Neuro IgG immunoblot for autoantibodies for neuronal antigens - The detection of these antibodies in sera of patients with neurological symptoms indicates the presence of a paraneoplastic neurological syndrome (PNS).
AA-neuro: Request Form from EU
AA-neuro: Request Form from USA
Serum-based tests : 2 ml SERUM. Centrifuge immediately after clotting. Keep at ambient temperature or 4°C for 24h. For longer periods, aliquot, freeze and ship frozen.

Heavy metals in urine (METU) 28-element urine profile
Heavy metals can also directly inhibit antioxidant enzymes like superoxide dismutase or glutathione reductase. This test is usually taken for chronic patient, ASD patients, chronic Lyme patients.
METU: Request Form from EU
METU: Request Form from USA
10-15 ml urine in tightly capped urine container, ambient temperature. Indicate if the sample is after chelation therapy.

Cannabinoid receptors expression testing (CBR)
Siniscalco et al. (J Autism Dev Disord. 2013; J Neuroinflammation 2014) reported that Cannabinoid receptor type 2 is up-regulated in peripheral blood mononuclear cells of children affected by autistic disorders and proposed CBR2 receptor as potential therapeutic target for the pharmacological management of the autism.
CBR: Request Form from EU
CBR: Request Form from USA
RNA-based tests : One TempusTM tube. Stable for 72 hours at ambient temperature. For longer periods freeze and ship at -20°C

Polymorphisms of Vitamin D receptor (GVDR)
Bsm1 and Fok1 are two SNP's in the gene coding for VDR (vitamin D receptor).VDR is not only involved in skeletal metabolism but also in modulation of immune response, regulation of cell proliferation and differentiation. VDR dysfunction has been linked with osteoarthritis, cancer, diabetes and cardiovascular disease.
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GVDR: Request Form from EU
GVDR: Request Form from USA
Whole blood-based tests : 2 ml whole blood in EDTA tube. Keep at ambient temperature or 4°C. Stable for 48 hours. Do not freeze