Elastase expression assay (ELAS)
Elastase is an inflammatory protease expressed in immune cells. Elastase contributes to the immune defense by inactivating foreign bacteria but causes damage to connective tissue and breaks down cytokines, immunoglobulins and immune cells receptors at the same time.
RNA-based tests : One TempusTM tube. Stable for 72 hours at ambient temperature. For longer periods freeze and ship at -20°C
- An excessive, chronic production of elastase is therefore detrimental. The expression of mRNA can be quantified as a specific marker of inflammation.
- Nijs J, Van Oosterwijck J, Meeus M, Lambrecht L, Metzger K, Frémont M, Paul L. Unravelling the nature of postexertional malaise in myalgic encephalomyelitis/chronic fatigue syndrome: the role of elastase, complement C4a and interleukin-1beta. J Intern Med. 2010 Apr;267(4):418-35. doi: 10.1111/j.1365-2796.2009.02178.x.
- Morrison TB1, Weis JH, Weis JJ. Borrelia burgdorferi outer surface protein A (OspA) activates and primes human neutrophils. J Immunol. 1997 May 15;158(10):4838-45.
No, we will send you an invoice once we receive your sample. All payment instructions are listed on the invoice. You can pay by wire transfer or credit card (VISA or Mastercard only). Please kindly note that checks are no longer accepted. The analysis report will be released only if the tests are paid.
It will take approx. 4 weeks to get the results from all tests, except for MSA (6 weeks) and CD56 and CD57 (48 -72 hours).
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