CD57+/CD3- absolute cell count
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CD57+/CD3- absolute cell count

CD57+/CD3- cells are a subset of NK cells. Their exact function is not well understood but differentiates them from CD56+ NK cells. The absolute number of CD57+/CD3- cells is low in patients suffering from chronic Lyme disease [Stricker et al. 2001].

CD57: Request Form from EU

CD57: Request Form from USA

Whole blood-based tests : 2 ml whole blood in EDTA tube. Keep at ambient temperature or 4°C. Stable for 48 hours. Do not freeze

Description

Patients with very low CD57 have significantly more co-infections and persistent immunologic defects than patients with higher counts. In patients that respond to antibiotic therapy, the number of cells come back to normal. Therefore, this is a useful marker to follow the effect of therapy.
Our study (Siniscalco et al, In Vivo 2016) showed that on 107 autistic patients enrolled, 73 (68.2%) of them showed CD57 below 100 cells/μl of whole blood (mean±SE 49.12±3.12), and among them 47 (64.4%) patients showed CD57 below the lower limit of the normal range (the normal range is considered 60-360 cells/μl of whole blood).

Data sheet
Do I need to prepay the test before receiving the kit?

No, we will send you an invoice once we receive your sample. All payment instructions are listed on the invoice. You can pay by wire transfer or credit card (VISA or Mastercard only). Please kindly note that checks are no longer accepted. The analysis report will be released only if the tests are paid.

What is the turnaround time for the tests?

Testing turnaround time is assay-dependent. Some results are available in 48h (like CD57 count, Phagotest, etc.), while some others need more time (like PCRs with sequencing confirmation). The results of analyses are delivered maximum 6 weeks after sample reception.

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