The Cunningham Panel™ helps clinicians identify whether a patient’s neurologic and/or psychiatric symptoms may be due to an infection-triggered basal ganglia encephalitis (BGE), which includes autoimmune neuropsychiatric syndromes such as PANS/PANDAS. Symptoms of BGE can mimic various mental illnesses.
This panel is composed of 5 tests: Anti-Dopamine D1 Receptor, Anti-Dopamine D2L Receptor, Anti-Lysoganglioside-GM1, Anti-Tubulin and Calcium/calmodulin-dependent protein kinase II (CaMKII). First four of the tests measure the levels of circulating autoantibodies in serum that are directed against and bind to, or block specific neuronal targets in the brain. Each of these autoantibody targets (Dopamine D1 and D2L receptors,
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