VEGF ELISA test in serum
VEGF has a great role in pathological conditions that are associated to autoimmune diseases such as in systemic lupus erythematosus, rheumatoid arthritis, and multiple sclerosis. Serum levels of VEGF correlate with disease activity in a large number of autoimmune diseases and fall with the use of standard therapy.
Serum-based tests : 2 ml SERUM. Centrifuge immediately after clotting. Keep at ambient temperature or 4°C for 24h. For longer periods, aliquot, freeze and ship frozen.
- Possible future therapeutic strategies in autoimmune diseases with the anti-VEGF or anti-VEGFR (receptor). So far, this therapy has been used in cancer and macular ocular degeneration in diabetes.
- Abnormally high levels of VEGF in a mold-free environment would suggest Bartonella infection.
- VEGF can go down in the presence of indoor molds.
- VEGF was also identified as major players in CIRS (Chronic Immune Response Syndrome) biotoxin pathway. The elevated cytokine levels in the capillaries attract white blood cells, leading to restricted blood flow and lower oxygen levels in the tissues (capillary hypoperfusion). Reduced VEGF leads to fatigue, muscle cramps and shortness of breath.
- Kempf VA, Volkmann B, Schaller M, Sander CA, Alitalo K, Riess T, Autenrieth IB. Evidence of a leading role for VEGF in Bartonella henselae-induced endothelial cell proliferations. Cell Microbiol. 2001 Sep;3(9):623-32. Cerimele F, Brown LF, Bravo F, Ihler GM, Kouadio P, Arbiser JL. Infectious angiogenesis: Bartonella bacilliformis infection results in endothelial production of 6 angiopoetin-2 and epidermal production of vascular endothelial growth factor. Am J Pathol. 2003 Oct;163(4):1321-7.
- Schulte B, Linke D, Klumpp S, Schaller M, Riess T, Autenrieth IB, Kempf VA. Bartonella quintana variably expressed outer membrane proteins mediate vascular endothelial growth factor secretion but not host cell adherence. Infect Immun. 2006 Sep;74(9):5003-13.
No, we will send you an invoice once we receive your sample. All payment instructions are listed on the invoice. You can pay by wire transfer or credit card (VISA or Mastercard only). Please kindly note that checks are no longer accepted. The analysis report will be released only if the tests are paid.
It will take approx. 4 weeks to get the results from all tests, except for MSA (6 weeks) and CD56 and CD57 (48 -72 hours).
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